Estradiol cream (vaginal) 2mg/ml (30ml)

$109.00

Delivery T&C

Estradiol Vaginal Cream (2mg/ml) is an HRT solution that may help restore moisture, elasticity, and comfort to vaginal tissues, relieving dryness, itching, burning, and painful intercourse that many women experience during perimenopause and menopause.

  • Localized vaginal therapy – 2mg/ml estradiol cream formulated for direct application to support vaginal tissue health.
  • Convenient 3-month supply – One 30ml tube provides approximately 3 months of typical use.
  • Gentle & effective – Designed for easy application with high bioavailability at the target area.
  • Clinically proven HRT support – Helps restore estrogen levels locally where needed most.
Compounded hormone preparation — not FDA-approved; not evaluated by the FDA for safety, efficacy, or quality. Prescription only after evaluation. Individual results vary.
Important risks (apply to estrogen therapy, including compounded forms): Estrogens increase the risk of cancer of the uterine lining, and have been associated with stroke, blood clots, breast cancer, and probable dementia in women 65 and older. Estrogen should not be used to prevent heart disease or dementia. Use the lowest effective dose for the shortest time consistent with your goals. Tell your provider about any history of cancer, blood clots, stroke, heart or liver disease, or unexplained vaginal bleeding.
These compounded preparations are not proven to be safer or more effective than FDA-approved hormone therapy.
  • Relieves vaginal dryness – Restores natural moisture and lubrication for greater comfort.
  • Improves tissue health – Helps restore thickness, elasticity, and strength of vaginal tissues.
  • Reduces discomfort – Decreases burning, itching, and irritation associated with menopause.
  • Supports intimate wellness – Enhances comfort during daily activities and intimacy.
  • Better overall quality of life – Helps women feel more comfortable and confident as part of a complete HRT program.

This vaginal estradiol cream is intended for localized HRT and is commonly used to treat symptoms of menopause and vaginal atrophy. Your provider will evaluate whether systemic hormone therapy is more appropriate for your individual symptoms and medical situation. 

Estradiol Cream + Progesterone Capsules – HRT Program (3 months))

Your prescription is filled by a licensed 503A compounding pharmacy after provider approval. Products are shipped discreetly via 2–3 day expedited shipping (cold chain where required). Most orders ship within 3–7 business days after consultation approval.
This product is compounded and not FDA-approved. It has not been evaluated by the FDA for safety, efficacy, or quality. It requires a valid prescription following a medical consultation with a licensed healthcare provider. Individual results may vary and are not guaranteed. Not intended to diagnose, treat, cure, or prevent any disease. Results depend on lifestyle factors and this product is not a substitute for medical care.

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A note about FDA compliance: *The doctor network may prescribe certain compounded drugs for the treatment of certain conditions,
subject to approval by a provider through the DefyAgeRX; however, even though our partner pharmacies use only pharmaceutical-grade
ingredients and are highly regulated, compounded prescriptions are not FDA approved. The appearance, contents, and dosage of the vial
may vary based on your personalized prescription, and individual results may vary.

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