NAD+ (nasal spray) 300 mg/ml (12 ml vial)

$189.00

Delivery T&C

NAD+ (Nicotinamide Adenine Dinucleotide) is the essential coenzyme that powers cellular energy production, repairs DNA, and activates the longevity pathways that keep your body functioning at a youthful level.

NAD⁺ (nasal spray) 300 mg/mL (12 mL vial) is a compounded intranasal formulation designed to support cellular energy and brain health by delivering NAD⁺ through the nasal mucosa, a route that may provide more direct access to the central nervous system than traditional oral forms. NAD⁺ is a critical cofactor in mitochondrial energy production and cellular repair pathways, and intranasal delivery is increasingly used in advanced wellness settings to complement protocols focused on cognitive clarity, fatigue, and healthy aging under medical supervision.
Each 12 mL multidose vial contains a 300 mg/mL NAD⁺ solution intended to be administered as measured sprays per nostril according to a provider‑directed schedule, often in cyclical “series” rather than continuous daily use. This therapy is typically paired with lifestyle strategies such as sleep optimization, nutrient support, and stress management, with dosing, frequency, and duration individualized by a licensed clinician based on tolerance and treatment goals.
Not Available in: CA, AL, AR, IN, MN

Supplementing with NAD+ (especially via injection or high-quality precursors) may help boost energy, support mental clarity, improve recovery, slow biological aging, and support better metabolism — making it a widely discussed compound for those interested in performance, anti-aging, and long-term vitality support.

  • Convenient nasal delivery of NAD+
  • Rapid brain and systemic absorption
  • Non-injectable option
Disclaimer:
Intranasal NAD⁺ (nicotinamide adenine dinucleotide) is a compounded preparation used off‑label to support energy metabolism, cognitive function, and healthy aging; it is not approved by the U.S. Food and Drug Administration (FDA) for these or any other indications. Current evidence for intranasal NAD⁺ comes mainly from small human studies, extrapolation from IV/oral NAD⁺ research, and mechanistic data; long‑term safety and efficacy have not been firmly established.
Information provided here is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Any decision to use NAD⁺ nasal spray should be made with a licensed healthcare provider who can assess individual risks (including nasal irritation, headache, or potential effects on blood pressure or heart rate), review other medications and conditions, and monitor response over time.
Defy Age RX does not dispense medication; no product is provided without a valid prescription. Individual results vary. Not medical advice.
  • Quick cognitive and energy boost
  • Neuroprotective effects
  • Easier daily use than injections
AspectNasal SpraySQ Injection
Bioavailability30–50% (variable by individual nasal factors like congestion)70–90% (more consistent)
Onset of EffectsPotentially quicker perceived (e.g., mental clarity in minutes to hours), but full benefits in days–weeksBuilds steadily (1–3 days with consistent use)
DurationShorter-lived (often 4–8 hours); requires more frequent dosingLonger-lasting/sustained (hours to days per dose)
Dose DeliveryLower concentrations typical; harder to achieve high systemic levelsHigher, more precise doses possible
ConsistencyMore variable (affected by technique, nasal health)More predictable and measurable
Best ForConvenience, maintenance, cognitive focus, and needle-averse usersTherapeutic/repletion needs, sustained energy, structured protocols

NAD+ and Glutathione – Both combat oxidative stress and boost cellular energy (NAD+ for sirtuins/mitochondria; GSH for direct ROS scavenging). Synergistic for energy, cognition, recovery, and anti-aging. Read Full Article

NAD+ and 5-Amino-1MQ + MOTS-c– a combination sometimes used for endurance and metabolic support. Both strongly support mitochondrial function and energy production; MOTS-c regulates metabolism, while 5-Amino-1MQ preserves NAD+. Read Full Article

NAD+ and TB500/ BPC-157  –  NAD+ enhances the cellular energy needed to drive the BPC/TB500 driven tissue rebuilding. Read Full Article

NAD+ + MOTS-c – a combination sometimes used for endurance, metabolic health, exercise performance, and mitochondrial optimization. Read Full Article

NAD+ + GHK-Cu → Skin/tissue regeneration + internal cellular energy/repair.

NAD+ + CJC-1295/Ipamorelin → GH axis support for muscle/recovery alongside mitochondrial energy.

NAD+ + Epitalon → Telomere support + broader cellular longevity

NAD+ + AOD9604 → Fat mobilization + metabolic energy for body recomposition

Prescribed after provider consultation and shipped from a 503A FDA-regulated pharmacy. Room-temperature shipping. Most orders fulfilled and shipped within 4–8 business days.
This product is compounded and not FDA-approved. It has not been evaluated by the FDA for safety, efficacy, or quality. It requires a valid prescription following a medical consultation with a licensed healthcare provider. Individual results may vary and are not guaranteed. Not intended to diagnose, treat, cure, or prevent any disease. Results depend on lifestyle factors and this product is not a substitute for medical care.

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A note about FDA compliance: *The doctor network may prescribe certain compounded drugs for the treatment of certain conditions,
subject to approval by a provider through the DefyAgeRX; however, even though our partner pharmacies use only pharmaceutical-grade
ingredients and are highly regulated, compounded prescriptions are not FDA approved. The appearance, contents, and dosage of the vial
may vary based on your personalized prescription, and individual results may vary.

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